2022 / 2021 / 2020

2022

  • Merlini A, Haberl M, Strauß J, Hildebrand L, Genc N, Franz J, Chilov D, Alitalo K, Flügel-Koch C, Stadelmann C, Flügel A, Odoardi F. Distinct roles of the meningeal layers in CNS autoimmunity, Nat Neurosci 2022 Jul;25(7):887-899,  http://dx.doi.org/10.1038/s41593-022-01108-3 (Pubmed)

  • Sudhakar Reddy Kalluri,Rajneesh Srivastava, Selin Kenet, Goutam K. Tanti, Klaus Dornmair, Jeffrey L. Bennett, Thomas Misgeld, Bernhard Hemmer, Matthias T. Wyss & Marina Herwerth . P2R Inhibitors Prevent Antibody-Mediated Complement Activation in an Animal Model of Neuromyelitis Optica. Neurotherapeutics (2022). https://doi.org/10.1007/s13311-022-01269-w (Pubmed)

  • Laura Empl, Alexandra Chovsepian, Maryam Chahin, Wing Yin Vanessa Kan, Julie Fourneau, Valérie Van Steenbergen, Sanofer Weidinger, Maite Marcantoni, Alexander Ghanem, Peter Bradley, Karl Klaus Conzelmann, Ruiyao Cai, Alireza Ghasemigharagoz, Ali Ertürk, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Sabine Liebscher & Florence M. Bareyre , Selective plasticity of callosal neurons in the adult contralesional cortex following murine traumatic brain injuryNat Commun 13, 2659 (2022). https://doi.org/10.1038/s41467-022-29992-0 (Pubmed)

  • Vincenti I, Page N, Steinbach K, Yermanos A, Lemeille S, Nunez N, Kreutzfeldt M, Klimek B, Di Liberto G, Egervari K, Piccinno M, Shammas G, Mariotte A, Fonta N, Liaudet N, Shlesinger D, Liuzzi AR, Wagner I, Saadi C, Stadelmann C, Reddy S, Becher B, Merkler D. Tissue-resident memory CD8+ T cells cooperate with CD4+ T cells to drive compartmentalized immunopathology in the CNS. Sci Transl Med. 2022 Apr 13;14(640):eabl6058. doi: 10.1126/scitranslmed.abl6058.  (Pubmed)

  • Asadollahi E, Trevisiol A, Saab AS, et al. Myelin lipids as nervous system energy reserves. bioRxiv; 2022. DOI: 10.1101/2022.02.24.481621. (Pubmed)

  • Bocchi R, Masserdotti G, Götz M. Direct neuronal reprogramming: Fast forward from new concepts toward therapeutic approaches. Neuron. 2022 Feb 2;110(3):366-393. (Pubmed)

  • Bauer A, Puglisi M, Nagl D, Schick JA, Werner T, Klingl A, El Andari J, Hornung V, Kessler H, Götz M, Grimm D, Brack-Werner R. Molecular Signature of Astrocytes for Gene Delivery by the Synthetic Adeno-Associated Viral Vector rAAV9P1. Adv Sci (Weinh). 2022 Apr 10:e2104979. (Pubmed)

  • Fourneau J, Bareyre FM. Semaphorin7A: its role in the control of serotonergic circuits and functional recovery following spinal cord injury. Neural Regen Res. 2022 May;17(5):959-962. (Pubmed)

  • Aljovic A, Zhao S, Chahin M, de la Rosa C, Van Steenbergen V, Kerschensteiner M,  Bareyre FM. A deep learning-based toolbox for Automated Limb Motion Analysis (ALMA) in murine models of neurological disorders. Commun Biol. 2022 Feb 15;5(1):131. (Pubmed)

  • Ehrenreich H, Garcia-Agudo LF, Steixner-Kumar AA, Wilke JBH, Butt UJ. Introducing the brain erythropoietin circle to explain adaptive brain hardware upgrade and improved performance. Mol Psychiatry. 2022 Apr 12:1–8.  (Pubmed)

  • Meschkat M, Steyer AM, Weil MT, Kusch K, Jahn O, Piepkorn L, Agüi-Gonzalez P, Phan NTN, Ruhwedel T, Sadowski B, Rizzoli SO, Werner HB, Ehrenreich H, Nave KA, Möbius W. White matter integrity in mice requires continuous myelin synthesis at the inner tongue. Nat Commun. 2022 Mar 4;13(1):1163. (Pubmed)

  • Sanchez-Gonzalez R, Koupourtidou C, Lepko T, Zambusi A, Novoselc KT, Durovic T, Aschenbroich S, Schwarz V, Breunig CT, Straka H, Huttner HB, Irmler M, Beckers J, Wurst W, Zwergal A, Schauer T, Straub T, Czopka T, Trümbach D, Götz M, Stricker SH, Ninkovic J. Innate Immune Pathways Promote Oligodendrocyte Progenitor Cell Recruitment to the Injury Site in Adult Zebrafish Brain. Cells. 2022 Feb 2;11(3):520. (Pubmed)

  • Linnerbauer M, Lößlein L, Farrenkopf D, Vandrey O, Tsaktanis T, Naumann U, Rothhammer V. Astrocyte-Derived Pleiotrophin Mitigates Late-Stage Autoimmune CNS Inflammation. Front Immunol. 2022 Jan 3;12:800128. (Pubmed)

  • Linnerbauer M, Lößlein L, Vandrey O, Tsaktanis T, Beer A, Naumann UJ, Panier F, Beyer T, Nirschl L, Kuramatsu JB, Winkler J, Quintana FJ, Rothhammer V. Intranasal delivery of a small-molecule ErbB inhibitor promotes recovery from acute and late-stage CNS inflammation. JCI Insight. 2022 Apr 8;7(7):e154824. (Pubmed)

  • Eira J, Magalhães J, Macedo N, Pero ME, Misgeld T, Sousa MM, Bartolini F, Liz MA. Transthyretin Promotes Axon Growth via Regulation of Microtubule Dynamics and Tubulin Acetylation. Front Cell Dev Biol. 2021 Nov 8;9:747699. (Pubmed)

  • Wang M, Misgeld T, Brill MS. Neural labeling and manipulation by neonatal intraventricular viral injection in mice. STAR Protoc. 2022 Jan 10;3(1):101081. (Pubmed)

  • Khalin I, Adarsh N, Schifferer M, Wehn A, Groschup B, Misgeld T, Klymchenko A, Plesnila N. Size-Selective Transfer of Lipid Nanoparticle-Based Drug Carriers Across the Blood Brain Barrier Via Vascular Occlusions Following Traumatic Brain Injury. Small. 2022 Apr 5:e2200302. (Pubmed)

  • Mar Bosch-Queralt, Vini Tiwari, Alkmini Damkou, Lenka Vaculčiaková, Ioannis Alexopoulos, Mikael Simons. A fluorescence microscopy-based protocol for volumetric measurement of lysolecithin lesion-associated de- and re-myelination in mouse brain, STAR Protocols, Volume 3, Issue 1, 2022. (Pubmed)

  • Leon Hosang, Roger Cugota Canals, Felicia Joy van der Flier, Jacqueline Hollensteiner, Rolf Daniel, Alexander Flügel & Francesca Odoardi, The lung microbiome regulates brain autoimmunity. Nature 603, 138–144 (2022). (Pubmed)

  • Lilian Aly, Christina Noll, Rebecca Wicklein, Elisabeth Wolf, Eva Feodora Romahn, Josphine Wauschkuhn, Sami Hosari, Christian Mardin, 
    Achim Berthele, Bernhard Hemmer, Thomas Korn, Benjamin Knier. Dynamics of Retinal Vessel Loss After Acute Optic Neuritis in Patients With Relapsing Multiple Sclerosis, , Neurol Neuroimmunol Neuroinflamm May 2022, 9 (3) e1159. (Pubmed)

  • Marina Herwerth, Selin Kenet, Martina Schifferer, Anne Winkler, Melanie Weber, Nicolas Snaidero, Mengzhe Wang, Melanie Lohrberg, Jeffrey L. Bennett, Christine Stadelmann, Bernhard Hemmer, Thomas Misgeld. A new form of axonal pathology in a spinal model of neuromyelitis opticaBrain, 2022; Feb 24:awac079. doi: 10.1093/brain/awac079. Epub ahead of print. (Pubmed)
     
  • Xiao Y, Petrucco L, Hoodless LJ, Portugues R, Czopka T. Oligodendrocyte precursor cells sculpt the visual system by regulating axonal remodeling. Nat Neurosci. 2022 Mar;25(3):280-284. doi: 10.1038/s41593-022-01023-7. Epub 2022 Mar 3. (Pubmed)

2021

  • Zhu J, Cao J, Liesz A, Roth S. A macrophage-T cell coculture model for severe tissue injury-induced T cell death. STAR Protoc. 2021 Dec 1;2(4):100983. doi: 10.1016/j.xpro.2021.100983. (Pubmed)

  • Zhang Y, Liesz A, Li P. Coming to the Rescue: Regulatory T Cells for Promoting Recovery After Ischemic Stroke. Stroke. 2021 Dec;52(12):e837-e841. doi: 10.1161/STROKEAHA.121.036072. (Pubmed)

  • Korn T, Hiltensperger M. Role of IL-6 in the commitment of T cell subsets. Cytokine. 2021 Oct;146:155654. doi: 10.1016/j.cyto.2021.155654. (Pubmed)

  • Aly L, Strauß EM, Feucht N, Weiß I, Berthele A, Mitsdoerffer M, Haass C, Hemmer B, Maier M, Korn T, Knier B. Optical coherence tomography angiography indicates subclinical retinal disease in neuromyelitis optica spectrum disorders. Mult Scler. 2022 Apr;28(4):522-531. doi: 10.1177/13524585211028831. (Pubmed)

  • Edgar JM, McGowan E, Chapple KJ, Möbius W, Lemgruber L, Insall RH, Nave KA, Boullerne A. Río-Hortega's drawings revisited with fluorescent protein defines a cytoplasm-filled channel system of CNS myelin. J Anat. 2021 Dec;239(6):1241-1255. doi: 10.1111/joa.13577. Epub 2021 Oct 28. (Pubmed)

  • Penkert H, Bertrand A, Tiwari V, Breimann S, Müller SA, Jordan PM, Gerl MJ, Klose C, Cantuti-Castelvetri L, Bosch-Queralt M, Levental I, Lichtenthaler SF, Werz O, Simons M. Proteomic and lipidomic profiling of demyelinating lesions identifies fatty acids as modulators in lesion recovery. Cell Rep. 2021 Oct 26;37(4):109898. doi: 10.1016/j.celrep.2021.109898. (Pubmed)

  • Begemann M, Gross O, Wincewicz D, Hardeland R, Daguano Gastaldi V, Vieta E, Weissenborn K, Miskowiak KW, Moerer O, Ehrenreich H. Addressing the 'hypoxia paradox' in severe COVID-19: literature review and report of four cases treated with erythropoietin analogues. Mol Med. 2021 Sep 26;27(1):120. doi: 10.1186/s10020-021-00381-5. (Pubmed)

  • Tuzlak S, Dejean AS, Iannacone M, Quintana FJ, Waisman A, Ginhoux F, Korn T, Becher B. Repositioning TH cell polarization from single cytokines to complex help. Nat Immunol. 2021 Oct;22(10):1210-1217. doi: 10.1038/s41590-021-01009-w. (Pubmed)

  • Gouna G, Klose C, Bosch-Queralt M, Liu L, Gokce O, Schifferer M, Cantuti-Castelvetri L, Simons M. TREM2-dependent lipid droplet biogenesis in phagocytes is required for remyelination. J Exp Med. 2021 Oct 4;218(10):e20210227. doi: 10.1084/jem.20210227. (Pubmed)

  • Fernandez Garcia-Agudo L, Steixner-Kumar AA, Curto Y, Barnkothe N, Hassouna I, Jähne S, Butt UJ, Grewe K, Weber MS, Green K, Rizzoli S, Nacher J, Nave KA, Ehrenreich H. Brain erythropoietin fine-tunes a counterbalance between neurodifferentiation and microglia in the adult hippocampus. Cell Rep. 2021 Aug 24;36(8):109548. doi: 10.1016/j.celrep.2021.109548. (Pubmed)

  • Wilke JBH, Hindermann M, Berghoff SA, Zihsler S, Arinrad S, Ronnenberg A, Barnkothe N, Steixner-Kumar AA, Röglin S, Stöcker W, Hollmann M, Nave KA, Lühder F, Ehrenreich H. Autoantibodies against NMDA receptor 1 modify rather than cause encephalitis. Mol Psychiatry. 2021 Dec;26(12):7746-7759. doi: 10.1038/s41380-021-01238-3. (Pubmed)

  • Van Steenbergen V, Bareyre FM. Chemogenetic approaches to unravel circuit wiring and related behavior after spinal cord injury. Exp Neurol. 2021 Nov;345:113839. doi: 10.1016/j.expneurol.2021.113839. (Pubmed)

  • Bergner CG, Genc N, Hametner S, Franz J, van der Meer F, Mitkovski M, Weber MS, Stoltenburg-Didinger G, Kühl JS, Köhler W, Brück W, Gärtner J, Stadelmann C. Concurrent axon and myelin destruction differentiates X-linked adrenoleukodystrophy from multiple sclerosis. Glia. 2021 Oct;69(10):2362-2377. doi: 10.1002/glia.24042. (Pubmed)

  • Liu L, Besson-Girard S, Ji H, Gehring K, Bulut B, Kaya T, Usifo F, Simons M, Gokce O. Dissociation of microdissected mouse brain tissue for artifact free single-cell RNA sequencing. STAR Protoc. 2021 Jun 10;2(2):100590. doi: 10.1016/j.xpro.2021.100590. (Pubmed)

  • Heindl S, Ricci A, Carofiglio O, Zhou Q, Arzberger T, Lenart N, Franzmeier N, Hortobagyi T, Nelson PT, Stowe AM, Denes A, Edbauer D, Liesz A. Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies. J Exp Med. 2021 Aug 2;218(8):e20202411. doi: 10.1084/jem.20202411. (Pubmed)

  • Riera-Tur I, Schäfer T, Hornburg D, Mishra A, da Silva Padilha M, Fernández-Mosquera L, Feigenbutz D, Auer P, Mann M, Baumeister W, Klein R, Meissner F, Raimundo N, Fernández-Busnadiego R, Dudanova I. Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity. Life Sci Alliance. 2021 Dec 21;5(3):e202101185. (Pubmed)

  • Brüser C, Keller-Findeisen J, Jakobs S. The TFAM-to-mtDNA ratio defines inner-cellular nucleoid populations with distinct activity levels. Cell Rep. 2021 Nov 23;37(8):110000. (PubMed

  • Arinrad S, Wilke JBH, Seelbach A, Doeren J, Hindermann M, Butt UJ, Steixner-Kumar AA, Spieth L, Ronnenberg A, Pan H, Berghoff SA, Hollmann M, Lühder F, Nave KA, Bechter K, Ehrenreich H. NMDAR1 autoantibodies amplify behavioral phenotypes of genetic white matter inflammation: a mild encephalitis model with neuropsychiatric relevance. Mol Psychiatry. 2021 Dec 6. (PubMed

  • Jesus Gil-Pulido, Núria Amézaga, Ivana Jorgacevic, Helga D Manthey, Melanie Rösch, Theresa Brand, Peter Cidlinsky, Sarah Schäfer, Andreas Beilhack, Antoine-Emmanuel Saliba, Kristina Lorenz, Louis Boon, Immo Prinz, Ari Waisman, Thomas Korn, Clément Cochain, Alma Zernecke, Interleukin-23 receptor expressing γδ T cells locally promote early atherosclerotic lesion formation and plaque necrosis in miceCardiovascular Research, Dec 2021;, cvab359 (PubMed

  • Kettwig M, Ternka K, Wendland K, Krüger DM, Zampar S, Schob C, Franz J, Aich A, Winkler A, Sakib MS, Kaurani L, Epple R, Werner HB, Hakroush S, Kitz J, Prinz M, Bartok E, Hartmann G, Schröder S, Rehling P, Henneke M, Boretius S, Alia A, Wirths O, Fischer A, Stadelmann C, Nessler S, Gärtner J. Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy. Nat Commun. 2021 Nov 11;12(1):6530. (PubMed

  • Peter Engerer, Eleni Petridou, Philip R. Williams, Sachihiro C.Suzuki, TakeshiYoshimatsu, Ruben Portugues, Thomas Misgeld, Leanne Godinho. Notch-mediated re-specification of neuronal identity during central nervous system development, Current Biology. Volume 31, Issue 21, 2021, Pages 4870-4878.e5, PMID: 34534440, DOI: 10.1016/j.cub.2021.08.049 (PubMed)

  • Jenny Meinhardt, Josefine Radke, Carsten Dittmayer, Jonas Franz, Carolina Thomas, Ronja Mothes, Michael Laue, Julia Schneider, Sebastian Brünink, Selina Greuel, Malte Lehmann, Olga Hassan, Tom Aschman, Elisa Schumann, Robert Lorenz Chua, Christian Conrad, Roland Eils, Werner Stenzel, Marc Windgassen, Larissa Rößler, Hans-Hilmar Goebel, Hans R Gelderblom, Hubert Martin, Andreas Nitsche, Walter J Schulz-Schaeffer, Samy Hakroush, Martin S Winkler, Björn Tampe, Franziska Scheibe, Péter Körtvélyessy, Dirk Reinhold, Britta Siegmund, Anja A Kühl, Sefer Elezkurtaj, David Horst, Lars Oesterhelweg, Michael Tsokos, Barbara Ingold-Heppner, Christine Stadelmann, Christian Drosten, Victor Max Corman , Helena Radbruch, Frank L Heppner.
    Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19.
    Nat Neurosci. 2021 Feb;24(2):168-175. doi: 10.1038/s41593-020-00758-5. Epub 2020 Nov 30. (PubMed)
  • Stefan A Berghoff, Lena Spieth, Ting Sun, Leon Hosang, Lennart Schlaphoff, Constanze Depp, Tim Düking, Jan Winchenbach, Jonathan Neuber, David Ewers, Patricia Scholz, Franziska van der Meer, Ludovico Cantuti-Castelvetri, Andrew O Sasmita, Martin Meschkat, Torben Ruhwedel, Wiebke Möbius, Roman Sankowski, Marco Prinz, Inge Huitinga, Michael W Sereda, Francesca Odoardi, Till Ischebeck, Mikael Simons, Christine Stadelmann-Nessler, Julia M Edgar, Klaus-Armin Nave, Gesine Saher. Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis.
    Nat Neurosci. 2021 Jan;24(1):47-60.doi: 10.1038/s41593-020-00757-6. Epub 2020 Dec 21. (PubMed)
  • Mehrnoosh Jafari, Adrian-Minh Schumacher, Nicolas Snaidero, Emily M Ullrich Gavilanes, Tradite Neziraj, Virág Kocsis-Jutka, Daniel Engels, Tanja Jürgens, Ingrid Wagner, Juan Daniel Flórez Weidinger, Stephanie S Schmidt, Eduardo Beltrán, Nellwyn Hagan, Lisa Woodworth, Dimitry Ofengeim, Joseph Gans, Fred Wolf, Mario Kreutzfeldt, Ruben Portugues, Doron Merkler, Thomas Misgeld, Martin Kerschensteiner.
    Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation.
    Nat Neurosci. 2021 Mar;24(3):355-367. doi: 10.1038/s41593-020-00780-7. Epub 2021 Jan 25. (PubMed)
  • Mengzhe Wang, Tatjana Kleele, Yan Xiao, Gabriela Plucinska, Petros Avramopoulos, Stefan Engelhardt, Markus H Schwab, Matthias Kneussel, Tim Czopka, Diane L Sherman, Peter J Brophy, Thomas Misgeld, Monika S Brill.
    Completion of neuronal remodeling prompts myelination along developing motor axon branches.
    J Cell Biol. 2021 Apr 5;220(4):e201911114. doi: 10.1083/jcb.201911114. (PubMed)
  • Minou Djannatian, Ulrich Weikert, Shima Safaiyan, Christoph Wrede, Cassandra Deichsel, Georg Kislinger, Torben Ruhwedel, Douglas S. Campbell, Tjakko van Ham, Bettina Schmid, Jan Hegermann, Wiebke Möbius, Martina Schifferer, Mikael Simons. Myelin biogenesis is associated with pathological ultrastructure that is resolved by microglia during development. bioRxiv 2021.02.02.429485 (PubMed)
  • Stefan Roth, Jiayu Cao, Vikramjeet Singh, Steffen Tiedt, Gabriel Hundeshagen, Ting Li, Julia D Boehme, Dhruv Chauhan, Jie Zhu, Alessio Ricci, Oliver Gorka, Yaw Asare, Jun Yang, Mary S Lopez, Markus Rehberg, Dunja Bruder, Shengxiang Zhang, Olaf Groß, Martin Dichgans, Veit Hornung, Arthur Liesz.
    Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade.
    Immunity. 2021 Mar 1;S1074-7613(21)00070-4. doi: 10.1016/j.immuni.2021.02.004. Online ahead of print. (PubMed)
  • Meike Mitsdörffer, Giovanni Di Liberto, Sarah Dötsch, Christopher Sie, Ingrid Wagner, Monika Pfaller, Mario Kreutzfeldt, Simon Fräßle, Lilian Aly, Benjamin Knier, Dirk H Busch, Doron Merkler, Thomas Korn.
    Formation and immunomodulatory function of meningeal B-cell aggregates in progressive CNS autoimmunity
    Brain. 2021 Mar 9;awab093. doi: 10.1093/brain/awab093. Online ahead of print. (Pubmed)
  • Kshiti Phulphagar, Lars I Kühn, Stefan Ebner, Annika Frauenstein, Jonathan J Swietlik, Jan Rieckmann, Felix Meissner.
    Proteomics reveals distinct mechanisms regulating the release of cytokines and alarmins during pyroptosis.
    Cell Rep. 2021 Mar 9;34(10):108826. doi: 10.1016/j.celrep.2021.108826. (Pubmed)
  • Umer Javed Butt, Imam Hassouna, Laura Fernandez Garcia-Agudo, Agnes A. Steixner-Kumar, Constanze Depp, Nadine Barnkothe, Matthias R. Zillmann, Anja Ronnenberg, Viktoria Bonet, Sandra Goebbels, Klaus-Armin Nave, Hannelore Ehrenreich.
    CaMKIIα Expressing Neurons to Report Activity-Related Endogenous Hypoxia upon Motor-Cognitive Challenge.
    Int. J. Mol. Sci. 2021, 22(6), 3164; (Pubmed)
  • Christoph Mahler, Adrian-Minh Schumacher, Marcus Unterrainer, Lena Kaiser, Thomas Höllbacher, Simon Lindner, Joachim Havla, Birgit Ertl-Wagner, Maximilian Patzig, Klaus Seelos, Julia Neitzel, Matthias Mäurer, Markus Krumbholz, Imke Metz, Wolfgang Brück, Christine Stadelmann, Doron Merkler, Achim Gass, Vladimir Milenkovic, Peter Bartenstein, Nathalie L Albert, Tania Kümpfel, Martin Kerschensteiner.
    TSPO PET imaging of natalizumab-associated progressive multifocal leukoencephalopathy.
    Brain. 2021 Mar 23;awab127. doi: 10.1093/brain/awab127. (Pubmed)
  • Anke Löhndorf, Leon Hosang, Wolfgang Dohle, Francesca Odoardi, Sissy-Alina Waschkowski, Anette Rosche, Andreas Bauche, Riekje Winzer, Eva Tolosa, Sabine Windhorst, Stephen Marry, Alexander Flügel, Barry V L Potter, Björn-Philipp Diercks, Andreas H Guse.
    2-Methoxyestradiol and its derivatives inhibit store-operated Ca 2+ entry in T cells: Identification of a new and potent inhibitor.
    Biochim Biophys Acta Mol Cell Res. 2021 May;1868(6):118988. doi: 10.1016/j.bbamcr.2021.118988. (Pubmed)
  • Anne Winkler, Claudia Wrzos, Michael Haberl, Marie-Theres Weil, Ming Gao, Wiebke Möbius, Francesca Odoardi, Dietmar R Thal, Mayland Chang, Ghislain Opdenakker, Jeffrey L Bennett, Stefan Nessler, Christine Stadelmann.
    Blood-brain barrier resealing in neuromyelitis optica occurs independently of astrocyte regeneration.
    J Clin Invest. 2021 Mar 1;131(5):e141694. doi: 10.1172/JCI141694. (Pubmed)
  • Mar Bosch-Queralt, Ludovico Cantuti-Castelvetri, Alkmini Damkou, Martina Schifferer, Kai Schlepckow, Ioannis Alexopoulos, Dieter Lütjohann, Christian Klose, Lenka Vaculčiaková, Takahiro Masuda, Marco Prinz, Kathryn M Monroe, Gilbert Di Paolo, Joseph W Lewcock, Christian Haass, Mikael Simons. Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination.
    Nat Metab. 2021 Feb;3(2):211-227. doi: 10.1038/s42255-021-00341-7. Epub 2021 Feb 18. (Pubmed)
  • Shima Safaiyan, Simon Besson-Girard, Tuğberk Kaya, Ludovico Cantuti-Castelvetri, Lu Liu, Hao Ji, Martina Schifferer, Garyfallia Gouna, Fumere Usifo, Nirmal Kannaiyan, Dirk Fitzner, Xianyuan Xiang, Moritz J Rossner, Matthias Brendel, Ozgun Gokce, Mikael Simons.
    White matter aging drives microglial diversity. Neuron. 2021 Apr 7;109(7):1100-1117.e10. doi: 10.1016/j.neuron.2021.01.027. Epub 2021 Feb 18. (Pubmed)
  • Umer Javed Butt, Agnes A Steixner-Kumar, Constanze Depp, Ting Sun, Imam Hassouna, Liane Wüstefeld, Sahab Arinrad, Matthias R Zillmann, Nadine Schopf, Laura Fernandez Garcia-Agudo, Leonie Mohrmann, Ulli Bode, Anja Ronnenberg, Martin Hindermann, Sandra Goebbels, Stefan Bonn, Dörthe M Katschinski, Kamilla W Miskowiak, Klaus-Armin Nave, Hannelore Ehrenreich. Hippocampal neurons respond to brain activity with functional hypoxia. Mol Psychiatry. 2021 Feb 9. doi: 10.1038/s41380-020-00988-w. Online ahead of print. (Pubmed)
  • Kristina Loy, Julie Fourneau, Ning Meng, Carmen Denecke, Giuseppe Locatelli, Florence M Bareyre. Semaphorin 7A restricts serotonergic innervation and ensures recovery after spinal cord injury. Cell Mol Life Sci. 2021 Mar;78(6):2911-2927. doi: 10.1007/s00018-020-03682-w. (Pubmed)
  • Timo Konen, Daniel Stumpf, Tim Grotjohann, Isabelle Jansen, Mariano Bossi, Michael Weber, Nickels Jensen, Stefan W Hell, Stefan Jakobs.
    The Positive Switching Fluorescent Protein Padron2 Enables Live-Cell Reversible Saturable Optical Linear Fluorescence Transitions (RESOLFT) Nanoscopy without Sequential Illumination Steps. ACS Nano. 2021 May 21. doi: 10.1021/acsnano.0c08207.  (Pubmed)

2020

  • Horst Penkert, Chris Lauber, Mathias J Gerl, Christian Klose, Markus Damm, Dirk Fitzner, Andrea Flierl-Hecht, Tania Kümpfel, Martin Kerschensteiner, Reinhard Hohlfeld, Lisa A Gerdes, Mikael Simons. Plasma lipidomics of monozygotic twins discordant for multiple sclerosis. Ann Clin Transl Neurol. 2020 Dec;7(12):2461-2466. doi: 10.1002/acn3.51216. Epub 2020 Nov 7. (PubMed)
  • Hong Pan, Agnes A Steixner-Kumar, Anna Seelbach, Nadine Deutsch, Anja Ronnenberg, Daniel Tapken, Nico von Ahsen, Marina Mitjans, Hans Worthmann, Ralf Trippe, Christina Klein-Schmidt, Nadine Schopf, Kristin Rentzsch, Martin Begemann, Jürgen Wienands, Winfried Stöcker, Karin Weissenborn, Michael Hollmann, Klaus-Armin Nave, Fred Lühder, Hannelore Ehrenreich.
    Multiple inducers and novel roles of autoantibodies against the obligatory NMDAR subunit NR1: a translational study from chronic life stress to brain injury. Mol Psychiatry. 2020 Feb 24. doi: 10.1038/s41380-020-0672-1. Online ahead of print. (PubMed)
  • Alessandro Zambusi, Özge Pelin Burhan, Rossella Di Giaimo, Bettina Schmid, Jovica Ninkovic. Granulins Regulate Aging Kinetics in the Adult Zebrafish Telencephalon. Cells. 2020 Feb 3;9(2):350. doi: 10.3390/cells9020350. (PubMed)
  • Chaitali Mukherjee, Tina Kling, Belisa Russo, Kerstin Miebach, Eva Kess, Martina Schifferer, Liliana D Pedro, Ulrich Weikert, Maryam K Fard, Nirmal Kannaiyan, Moritz Rossner, Marie-Louise Aicher, Sandra Goebbels, Klaus-Armin Nave, Eva-Maria Krämer-Albers, Anja Schneider, Mikael Simons.
    Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain. Cell Metab. 2020 Aug 4;32(2):259-272.e10. doi: 10.1016/j.cmet.2020.05.019. Epub 2020 Jun 11. (PubMed)
  • Katherine D LaClair, Qihui Zhou, Meike Michaelsen, Benedikt Wefers, Monika S Brill, Aleksandar Janjic, Birgit Rathkolb, Daniel Farny, Mikolaj Cygan, Martin Hrabe de Angelis, Wolfgang Wurst, Manuela Neumann, Wolfgang Enard, Thomas Misgeld, Thomas Arzberger, Dieter Edbauer.
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