{"id":2469,"date":"2024-01-30T14:19:27","date_gmt":"2024-01-30T13:19:27","guid":{"rendered":"https:\/\/www.sfb274.de\/?post_type=project&#038;p=2469"},"modified":"2026-05-08T15:12:49","modified_gmt":"2026-05-08T13:12:49","slug":"c04","status":"publish","type":"project","link":"https:\/\/www.sfb274.de\/en\/project\/c04\/","title":{"rendered":"Brain network remodelling as a checkpoint of recovery after acute retinal injury"},"content":{"rendered":"<style>.kb-row-layout-id2469_48ee44-4e > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id2469_48ee44-4e > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id2469_48ee44-4e > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:var(--global-kb-spacing-sm, 1.5rem);padding-bottom:var(--global-kb-spacing-sm, 1.5rem);grid-template-columns:minmax(0, calc(45% - ((var(--global-kb-gap-md, 2rem) * 1 )\/2)))minmax(0, calc(55% - ((var(--global-kb-gap-md, 2rem) * 1 )\/2)));}.kb-row-layout-id2469_48ee44-4e > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id2469_48ee44-4e > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id2469_48ee44-4e > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id2469_48ee44-4e alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-2-columns kt-row-layout-equal kt-tab-layout-row kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column2469_5387c4-54 > .kt-inside-inner-col,.kadence-column2469_5387c4-54 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column2469_5387c4-54 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column2469_5387c4-54 > .kt-inside-inner-col{flex-direction:column;}.kadence-column2469_5387c4-54 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column2469_5387c4-54 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column2469_5387c4-54{position:relative;}@media all and (max-width: 1024px){.kadence-column2469_5387c4-54 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column2469_5387c4-54 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column2469_5387c4-54\"><div class=\"kt-inside-inner-col\"><style>.kb-image2469_e5a937-87 .kb-image-has-overlay:after{opacity:0.3;}<\/style>\n<figure class=\"wp-block-kadence-image kb-image2469_e5a937-87 size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"823\" height=\"720\" src=\"https:\/\/www.sfb274.de\/wp-content\/uploads\/2024\/01\/C04-Graphical-Abstract-Godinho-Portugues_v3-01-823x720.png\" alt=\"\" class=\"kb-img wp-image-2391\" srcset=\"https:\/\/www.sfb274.de\/wp-content\/uploads\/2024\/01\/C04-Graphical-Abstract-Godinho-Portugues_v3-01-823x720.png 823w, https:\/\/www.sfb274.de\/wp-content\/uploads\/2024\/01\/C04-Graphical-Abstract-Godinho-Portugues_v3-01-411x360.png 411w, https:\/\/www.sfb274.de\/wp-content\/uploads\/2024\/01\/C04-Graphical-Abstract-Godinho-Portugues_v3-01-768x672.png 768w, https:\/\/www.sfb274.de\/wp-content\/uploads\/2024\/01\/C04-Graphical-Abstract-Godinho-Portugues_v3-01.png 945w\" sizes=\"auto, (max-width: 823px) 100vw, 823px\" \/><\/figure>\n<\/div><\/div>\n\n\n<style>.kadence-column2469_87ca7d-a6 > .kt-inside-inner-col,.kadence-column2469_87ca7d-a6 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column2469_87ca7d-a6 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column2469_87ca7d-a6 > .kt-inside-inner-col{flex-direction:column;}.kadence-column2469_87ca7d-a6 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column2469_87ca7d-a6 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column2469_87ca7d-a6{position:relative;}@media all and (max-width: 1024px){.kadence-column2469_87ca7d-a6 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column2469_87ca7d-a6 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column2469_87ca7d-a6\"><div class=\"kt-inside-inner-col\">\n<h2 class=\"wp-block-heading\">Summary<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Circuit remodelling following brain trauma represents compensatory changes that may restore lost function. We investigate network remodelling in the visual system of zebrafish as it allows an unbiased systems-based approach to identify the changes and checkpoints that enable compensatory circuit repair. After ablating specific retinal photoreceptors, we will probe changes in network activity and structural remodelling in central visual circuits, as well as investigate the contribution of glial cells to synaptic plasticity to reveal the mechanisms mediating the recovery of visual function.<\/p>\n\n\n\n<p class=\"has-text-align-right has-theme-palette-7-color has-text-color has-link-color wp-elements-69bacf0f7a5d8dd4545d029e1393eb18 wp-block-paragraph\"><a href=\"https:\/\/gepris.dfg.de\/gepris\/projekt\/434477274\" target=\"_blank\" rel=\"noreferrer noopener\">DFG GEPRIS<\/a><\/p>\n<\/div><\/div>\n\n<\/div><\/div>\n\n<style>.kb-row-layout-id2469_ecdcd9-62 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id2469_ecdcd9-62 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id2469_ecdcd9-62 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:var(--global-kb-spacing-sm, 1.5rem);padding-bottom:var(--global-kb-spacing-sm, 1.5rem);grid-template-columns:minmax(0, calc(40% - ((var(--global-kb-gap-md, 2rem) * 2 )\/3)))minmax(0, calc(10% - ((var(--global-kb-gap-md, 2rem) * 2 )\/3)))minmax(0, calc(50% - ((var(--global-kb-gap-md, 2rem) * 2 )\/3)));}.kb-row-layout-id2469_ecdcd9-62 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id2469_ecdcd9-62 > .kt-row-column-wrap > div:not(.added-for-specificity){grid-column:initial;}}@media all and (max-width: 1024px){.kb-row-layout-id2469_ecdcd9-62 > .kt-row-column-wrap{grid-template-columns:repeat(3, minmax(0, 1fr));}}@media all and (max-width: 767px){.kb-row-layout-id2469_ecdcd9-62 > .kt-row-column-wrap > div:not(.added-for-specificity){grid-column:initial;}.kb-row-layout-id2469_ecdcd9-62 > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id2469_ecdcd9-62 alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-3-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column2469_50681c-29 > .kt-inside-inner-col,.kadence-column2469_50681c-29 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column2469_50681c-29 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column2469_50681c-29 > .kt-inside-inner-col{flex-direction:column;}.kadence-column2469_50681c-29 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column2469_50681c-29 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column2469_50681c-29{position:relative;}@media all and (max-width: 1024px){.kadence-column2469_50681c-29 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column2469_50681c-29 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column2469_50681c-29\"><div class=\"kt-inside-inner-col\">\n<p class=\"has-text-align-right wp-block-paragraph\"><a href=\"https:\/\/www.sfb274.de\/en\/project\/c03\/\">&lt;&lt;  Previous Project<\/a><\/p>\n<\/div><\/div>\n\n\n<style>.kadence-column2469_87efbe-da > .kt-inside-inner-col,.kadence-column2469_87efbe-da > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column2469_87efbe-da > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column2469_87efbe-da > .kt-inside-inner-col{flex-direction:column;}.kadence-column2469_87efbe-da > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column2469_87efbe-da > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column2469_87efbe-da{position:relative;}@media all and (max-width: 1024px){.kadence-column2469_87efbe-da > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column2469_87efbe-da > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column2469_87efbe-da\"><div class=\"kt-inside-inner-col\">\n<p class=\"has-text-align-center wp-block-paragraph\"><strong>|<\/strong><\/p>\n<\/div><\/div>\n\n\n<style>.kadence-column2469_be00f6-e9 > .kt-inside-inner-col,.kadence-column2469_be00f6-e9 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column2469_be00f6-e9 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column2469_be00f6-e9 > .kt-inside-inner-col{flex-direction:column;}.kadence-column2469_be00f6-e9 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column2469_be00f6-e9 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column2469_be00f6-e9{position:relative;}@media all and (max-width: 1024px){.kadence-column2469_be00f6-e9 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column2469_be00f6-e9 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column2469_be00f6-e9\"><div class=\"kt-inside-inner-col\">\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.sfb274.de\/en\/project\/c05\/\">Next Project  >><\/a><\/p>\n<\/div><\/div>\n\n<\/div><\/div>","protected":false},"template":"","meta":{"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":""},"project-area":[18],"class_list":["post-2469","project","type-project","status-publish","hentry","project-area-c-neuronal-checkpoints-of-cns-recovery"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Brain network remodelling as a checkpoint of recovery after acute retinal injury - SFB-Transregio 274<\/title>\n<meta name=\"description\" content=\"We investigate network remodelling in the visual system 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