Adaptive digital tissue deconvolution.
doi: 10.1093/bioinformatics/btae263
CODEX: COunterfactual Deep learning for the in silico EXploration of cancer cell line perturbations.
doi: 10.1093/bioinformatics/btae261
TFEB activation hallmarks antigenic experience of B lymphocytes and directs germinal center fate decisions
doi: 10.1038/s41467-024-51166-3
Combining array tomography with electron tomography provides insights into leakiness of the blood-brain barrier in mouse cortex.
doi: 10.7554/eLife.90565
Innate immune memory after brain injury drives inflammatory cardiac dysfunction
doi: 10.1016/j.cell.2024.06.028
Astrocytes adopt a progenitor-like migratory strategy for regeneration in adult brain
doi: 10.1101/2024.05.18.594292
Erythropoietin restrains the inhibitory potential of interneurons in the mouse hippocampus
doi: 10.1038/s41380-024-02528-2
Toward identifying key mechanisms of progression in multiple sclerosis
doi: 10.1016/j.tins.2023.11.005
Association of retinal vessel pathology and brain atrophy in relapsing-remitting multiple sclerosis
doi: 10.3389/fimmu.2023.1284986
Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity
doi: 10.1073/pnas.2309205120
The role of intrathecal free light chains kappa for the detection of autoimmune encephalitis in subacute onset neuropsychiatric syndromes
doi: 10.1038/s41598-023-44427-6
Reactive oxygen species produced by myeloid cells in psoriasis as a potential biofactor contributing to the development of vascular inflammation
doi: 10.1002/biof.1949
Foxp3+ regulatory T cells in the central nervous system and other nonlymphoid tissues
doi: 10.1002/eji.202250227
Evaluation of Novel Enhancer Compounds in Gentamicin-Mediated Readthrough of Nonsense Mutations in Rett Syndrome
doi: 10.3390/ijms241411665
3d Virtual Histology Reveals Pathological Alterations of Cerebellar Granule Cells in Multiple Sclerosis
doi: 10.1016/j.neuroscience.2023.04.002
Rapid differentiation of MOGAD and MS after a single optic neuritis
doi: 10.1007/s00415-024-12666-w
Oligodendroglial fatty acid metabolism as a central nervous system energy reserve
doi: 10.1038/s41593-024-01749-6
Accelerometer-derived movement features as predictive biomarkers for muscle atrophy in neurocritical care: a prospective cohort study
doi: 10.1186/s13054-024-05067-y
Diagnostic accuracy and confounders of vagus nerve ultrasound in amyotrophic lateral sclerosis—a single-center case series and pooled individual patient data meta-analysis
doi: 10.1007/s00415-024-12601-z
Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system
doi: 10.1016/j.immuni.2024.07.001
Neurofilament Light Chain Serum Levels Mirror Age and Disability in Secondary Progressive Multiple Sclerosis
doi: 10.1212/nxi.0000000000200279
Direct neuronal reprogramming of mouse astrocytes is associated with multiscale epigenome remodeling and requires Yy1
doi: 10.1038/s41593-024-01677-5
T cell-mediated microglial activation triggers myelin pathology in a mouse model of amyloidosis
doi: 10.1038/s41593-024-01682-8
Tolerability and first hints for potential efficacy of motor‐cognitive training under inspiratory hypoxia in health and neuropsychiatric disorders: A translational viewpoint
doi: 10.1002/nep3.47
Multiple sclerosis and the intestine: Chasing the microbial offender
doi: 10.1111/imr.13357
Retinal small vessel pathology is associated with disease burden in multiple sclerosis
doi: 10.1177/13524585241247775
Optical coherence tomography angiography suggests different retinal pathologies in multiple sclerosis and Sjögren’s syndrome
doi: 10.1007/s00415-024-12414-0
BTK inhibition limits microglia-perpetuated CNS inflammation and promotes myelin repair
doi: 10.1007/s00401-024-02730-0
Cerebellar Ex Vivo Magnetic Resonance Imaging at its Feasibility Limit: Up to 77-Microns Isotropic Resolution using Low-Bandwidth Balanced Steady State Free Precession (LoBa-bSSFP) Sequences and 3T Standard Equipment
doi: 10.1101/2024.04.18.589707
Fluorogenic Chemical Probes for Wash-free Imaging of Cell Membrane Damage in Ferroptosis, Necrosis, and Axon Injury
doi: 10.1021/jacs.3c07662
Shared inflammatory glial cell signature after stab wound injury, revealed by spatial, temporal, and cell-type-specific profiling of the murine cerebral cortex
doi: 10.1038/s41467-024-46625-w
Gut–Brain Interactions and Their Impact on Astrocytes in the Context of Multiple Sclerosis and Beyond
doi: 10.3390/cells13060497
Polyglutamylation of microtubules drives neuronal remodeling
doi: 10.1101/2024.03.11.584412
An Animal Model for Chronic Meningeal Inflammation and Inflammatory Demyelination of the Cerebral Cortex
doi: 10.3390/ijms241813893
Risk factors and outcomes after interruption of sedation in subarachnoid hemorrhage (ROUTINE-SAH) -a retrospective cohort study
doi: 10.3389/fneur.2024.1363107
The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology
doi: 10.1038/s41590-024-01756-6
Differential Role of Factor XIII in Acute Myocardial Infarction and Ischemic Stroke
doi: 10.3390/biomedicines12030497
Plasma Lipidomic Profiling Using Mass Spectrometry for Multiple Sclerosis Diagnosis and Disease Activity Stratification (LipidMS)
doi: 10.3390/ijms25052483
Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer’s disease model mice
doi: 10.1038/s41593-024-01730-3
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4
doi: 10.1038/s41586-024-07079-8
In-situ architecture of the human prohibitin complex
doi: 10.1101/2024.02.14.579514
Validating a minipig model of reversible cerebral demyelination using human diagnostic modalities and electron microscopy
doi: 10.1016/j.ebiom.2024.104982
IntelliR: A comprehensive and standardized pipeline for automated profiling of higher cognition in mice
doi: 10.1101/2024.01.25.577156
Direct neuronal reprogramming of NDUFS4 patient cells identifies the unfolded protein response as a novel general reprogramming hurdle
doi: 10.1016/j.neuron.2023.12.020
Long term follow-up in GAMT deficiency – Correlation of therapy regimen, biochemical and in vivo brain proton MR spectroscopy data
doi: 10.1016/j.ymgmr.2024.101053
L-Lactate Treatment at 24 h and 48 h after Acute Experimental Stroke Is Neuroprotective via Activation of the L-Lactate Receptor HCA1
doi: 10.3390/ijms25021232
Folate receptor α deficiency – Myelin‐sensitive MRI as a reliable biomarker to monitor the efficacy and long‐term outcome of a new therapeutic approach
doi: 10.1002/jimd.12713
CSF and venous blood flow from childhood to adulthood studied by real-time phase-contrast MRI
doi: 10.1007/s00381-024-06275-1
Characteristics, Prevalence, and Clinical Relevance of Juxtacortical Paramagnetic Rims in Patients With Multiple Sclerosis
doi: 10.1212/wnl.0000000000207966
Injury-specific factors in the cerebrospinal fluid regulate astrocyte plasticity in the human brain
doi: 10.1038/s41591-023-02644-6
Sekundärprophylaxe des ischämischen Schlaganfalls
doi: 10.1007/s00108-023-01615-w
Early Neuroaxonal Damage in Neurologic Disorders Associated With GAD65 Antibodies
doi: 10.1212/nxi.0000000000200176
Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions
doi: 10.1038/s42255-023-00838-3
A genome-wide in vivo CRISPR screen identifies essential regulators of T cell migration to the CNS in a multiple sclerosis model
doi: 10.1038/s41593-023-01432-2
PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation
doi: 10.1038/s41467-023-40982-8
Fibroblast growth factor 9 (FGF9) mediated neurodegeneration: implications for progressive multiple sclerosis?
doi: 10.1111/nan.12935
Expanding the function of oligodendrocytes to brain energy metabolism
doi: 10.1016/j.conb.2023.102782
Erythropoietin re-wires cognition-associated transcriptional networks
doi: 10.1038/s41467-023-40332-8
Regulation of the programmed cell death protein 1/programmed cell death ligand 1axis in relapsing-remitting multiple sclerosis
doi: 10.1093/braincomms/fcad206
Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease
doi: 10.1126/science.abn6366
Proceedings of the National Academy of Sciences of the United States of America
2023
Pubmed
Open AccessJournal Article
Visualizing the activation of encephalitogenic T cells in the ileal lamina propria by in vivo two-photon imaging
doi: 10.1073/pnas.2302697120
Spatial Transcriptomics-correlated Electron Microscopy maps transcriptional and ultrastructural responses to brain injury
doi: 10.1038/s41467-023-39447-9
Tipping points in neurodegeneration
doi: 10.1016/j.neuron.2023.05.031
Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease
doi: 10.1038/s41593-023-01366-9
Ex vivo immunocapture and functional characterization of cell-type-specific mitochondria using MitoTag mice
doi: 10.1038/s41596-023-00831-w
Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease
doi: 10.1038/s41586-023-06120-6
2-Methoxyestradiol-3,17-O,O-bis-sulfamate inhibits store-operated Ca(2+) entry in T lymphocytes and prevents experimental autoimmune encephalomyelitis.
doi: 10.1016/j.bbamcr.2023.119485
Neural dynamics and architecture of the heading direction circuit in zebrafish.
doi: 10.1038/s41593-023-01308-5
Remyelination by surviving oligodendrocytes is inefficient in the inflamed mammalian cortex.
doi: 10.1016/j.neuron.2023.03.031
Myelination generates aberrant ultrastructure that is resolved by microglia.
doi: 10.1083/jcb.202204010
Shared inflammatory glial cell signature after brain injury, revealed by spatial, temporal and cell-type-specific profiling of the murine cerebral cortex
doi: 10.1101/2023.02.24.529840
Exploiting moderate hypoxia to benefit patients with brain disease: Molecular mechanisms and translational research in progress
doi: 10.1002/nep3.15
Antibodies Against Glutamic Acid Decarboxylase 65 Are Locally Produced in the CSF and Arise During Affinity Maturation
doi: 10.1212/nxi.0000000000200090
Membrane lipid remodeling modulates γ-secretase processivity
doi: 10.1016/j.jbc.2023.103027
Drug screening identifies tazarotene and bexarotene as therapeutic agents in multiple sulfatase deficiency
doi: 10.15252/emmm.202114837
Targeting B Cells and Microglia in Multiple Sclerosis With Bruton Tyrosine Kinase Inhibitors
doi: 10.1001/jamaneurol.2022.5332
Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2
doi: 10.1016/j.celrep.2021.109409
Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain
doi: 10.1101/2022.05.09.491019
Targeted metabolomics revealed changes in phospholipids during the development of neuroinflammation in Abcd1tm1Kds mice and X‐linked adrenoleukodystrophy patients
doi: 10.1002/jimd.12389
LC-MS Based Platform Simplifies Access to Metabolomics for Peroxisomal Disorders
doi: 10.3390/metabo11060347
Urinary Levels of SARS-CoV-2 Nucleocapsid Protein Associate With Risk of AKI and COVID-19 Severity: A Single-Center Observational Study
doi: 10.3389/fmed.2021.644715
The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells
doi: 10.1038/s41593-021-00926-1
Neuronal replacement: Concepts, achievements, and call for caution
doi: 10.1016/j.conb.2021.03.014
Correction: Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2
doi: 10.1016/j.celrep.2021.109571
TUNAR lncRNA Encodes a Microprotein that Regulates Neural Differentiation and Neurite Formation by Modulating Calcium Dynamics
doi: 10.3389/fcell.2021.747667
Astrocyte-Derived Pleiotrophin Mitigates Late-Stage Autoimmune CNS Inflammation
doi: 10.3389/fimmu.2021.800128
White matter integrity in mice requires continuous myelin synthesis at the inner tongue
doi: 10.1038/s41467-022-28720-y
Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43
doi: 10.7554/elife.75230
Transthyretin Promotes Axon Growth via Regulation of Microtubule Dynamics and Tubulin Acetylation
doi: 10.3389/fcell.2021.747699
Neural labeling and manipulation by neonatal intraventricular viral injection in mice
doi: 10.1016/j.xpro.2021.101081
Semaphorin7A: its role in the control of serotonergic circuits and functional recovery following spinal cord injury
doi: 10.4103/1673-5374.324828
Oligodendrocyte precursor cells sculpt the visual system by regulating axonal remodeling
doi: 10.1038/s41593-022-01023-7
Proceedings of the National Academy of Sciences of the United States of America
2022
Pubmed
Open AccessJournal Article
The glioblastoma multiforme tumor site promotes the commitment of tumor-infiltrating lymphocytes to the TH17 lineage in humans
doi: 10.1073/pnas.2206208119
Aquaporin-4 prevents exaggerated astrocytosis and structural damage in retinal inflammation
doi: 10.1007/s00109-022-02202-6
Cellular and Molecular Determinants of Retinal Cell Fate
doi: 10.1146/annurev-vision-100820-103154
Brain injury environment critically influences the connectivity of transplanted neurons
doi: 10.1126/sciadv.abg9445
Probing cell identity hierarchies by fate titration and collision during direct reprogramming
doi: 10.15252/msb.202211129
Reparative inflammation in multiple sclerosis
doi: 10.1016/j.smim.2022.101630
Hemorrhagic lesion with detection of infected endothelial cells in human bornavirus encephalitis
doi: 10.1007/s00401-022-02442-3
The Gut-Brain Axis in Inflammatory Bowel Disease – Current and Future Perspectives
doi: 10.3390/ijms22168870
