CD8+ T cells drive inflammation in both prodromal and established MS
Exciting new research is shedding light on the role of CD8+ T cells in MS, revealing how they contribute to disease progression.Using single-cell RNA sequencing and
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Oligodendroglial fatty acid metabolism as a central nervous system energy reserve
A recent study by the labs of our members Klaus-Armin Nave and Hannelore Ehrenreich published in Nature Neuroscience uncovers a key role of oligodendroglial cells in
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TFEB governs B-lymphoid fate decisions.
TFEB activation hallmarks antigenic experience of B lymphocytes and directs germinal center fate decisions Antigenic stimulation triggers TFEB to move into the nucleus, where it can
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Key mechanisms identified for improving astrocyte-to-neuron reprogramming
Researchers from the Ludwig Maximilian University of Munich (LMU) made significant progress in unraveling novel mechanisms of glia-to-neuron conversion. By using novel methods in epigenome profiling,
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Amyloidosis triggers age-related oligodendrocyte and myelin damage
Age-related myelin damage leads to white matter inflammation, but its impact on chronic neurodegenerative diseases remains unclear. A recent study reveals that amyloidosis alone can cause
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Possible trigger for autoimmune diseases discovered
Immune system: B cells teach T cells which targets must not be attacked
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