A recent study published in Nature Neuroscience reveals that oligodendrocytes, the myelinating cells of the central nervous system (CNS), play a crucial role in energy metabolism by utilizing fatty acids to support white matter function. This continuous lipid metabolism provides an energy reserve essential for maintaining axonal health, especially during glucose scarcity. Key Findings: Implications:…
Congratulations to Anna-Sophia Wahl for obtaining a European Research Council (ERC) Starting Grant! From the Ludwig-Maximilians-Universität München Newsroom:“In the ARISE (Activate Repair In StrokE) project, Anna-Sophia Wahl wants to discover fundamental principles how the brain orchestrates the cellular response [to launch self-repair mechanisms after damage] and how it can be further improved. Using state- of the art…
After her outstanding contributions to research and teaching, our project leader Florence Bareyre has been awarded an adjunct professorship.
NeuroCamp Munich is a 2-week summer school where students in the (pen-)ultimate year of high school can experience what it is like to be a neuroscientist. Through a week of lectures covering various aspects of neuroscience, followed by a week of experimenting in the lab, the students get a true feel of a life in…
Lecture Series
Researchers from the Ludwig Maximilian University of Munich (LMU) made significant progress in unraveling novel mechanisms of glia-to-neuron conversion. By using novel methods in epigenome profiling, they identify a posttranslational modification of Neurogenin2 which profoundly impacts epigenetic rewiring and the improvement in neuronal programming. Specifically, they identified a novel protein as key player in this…
Age-related myelin damage leads to white matter inflammation, but its impact on chronic neurodegenerative diseases remains unclear. A recent study reveals that amyloidosis alone can cause age-related oligodendrocyte and myelin damage in mouse models of Alzheimer’s disease. The research team discovered that CD8 T cells contribute to neurodegenerative diseases associated with amyloidosis by abnormally activating…
Visit the stand of the Network of German Neurocenters at FENS from 25 – 29 June in Vienna, Austria http://www.neurocenters-germany.de/
The TRR 274 was present once again at the second edition of the Munich Brain Day. The event aimed at bringing the neuroscientist community in Munich together is co-organized by TRR project leader Ruben Portugues. This year, Simon Schäfer and Mikael Simons from our TRR were invited speakers. During the poster session, several of our…
As part of public outreach of the TRR 274, The Institute of Neuroimmunology and Multiple Sclerosis Research (IMSF, headed by Prof. Alexander Flügel) explained how immune cells migrate into the brain and spinal cord and can be visualized directly in the tissue. Under guidance, the students were able to embed, cut, stain and microscope tissue…
Immune system: B cells teach T cells which targets must not be attacked
The BMC Open Day at the Biomedical Centre on 16th March 2024 attracted more than 2000 visitors to Martinsried. A wide range of booths, lectures and activities gave everyone the opportunity to experience research at first hand. Also our consortium was present to inform the public of our aims and goals. Letting people know that…
