Author: Camilla Giudici

  • Diversity Symposium at the BMC Munich

    Last week, the BMC Diversity Initiative held its first-ever diversity symposium, featuring three inspiring speakers who shared their career journeys and the challenges they’ve overcome to get where they are today. Speakers (from left to right): In research, diverse perspectives drive innovative ideas. Science thrives on curiosity and creativity,because the best answers are never straightforward….

  • TFEB governs B-lymphoid fate decisions.

    TFEB activation hallmarks antigenic experience of B lymphocytes and directs germinal center fate decisions Antigenic stimulation triggers TFEB to move into the nucleus, where it can either promote B cell survival or lead to apoptosis depending on T cell help. Without T cell support, TFEB increases pro-apoptotic proteins, leading to cell death. But with T…

  • Oligodendroglial fatty acid metabolism as a central nervous system energy reserve

    A recent study published in Nature Neuroscience reveals that oligodendrocytes, the myelinating cells of the central nervous system (CNS), play a crucial role in energy metabolism by utilizing fatty acids to support white matter function. This continuous lipid metabolism provides an energy reserve essential for maintaining axonal health, especially during glucose scarcity. Key Findings: Implications:…

  • ERC Starting Grant for Anna-Sophia Wahl

    Congratulations to Anna-Sophia Wahl for obtaining a European Research Council (ERC) Starting Grant! From the Ludwig-Maximilians-Universität München Newsroom:“In the ARISE (Activate Repair In StrokE) project, Anna-Sophia Wahl wants to discover fundamental principles how the brain orchestrates the cellular response [to launch self-repair mechanisms after damage] and how it can be further improved. Using state- of the art…

  • Congratulations Professor Bareyre!

    After her outstanding contributions to research and teaching, our project leader Florence Bareyre has been awarded an adjunct professorship.

  • TRR 274 Soft Skill Workshop at NeuroCamp Munich 2024

    NeuroCamp Munich is a 2-week summer school where students in the (pen-)ultimate year of high school can experience what it is like to be a neuroscientist. Through a week of lectures covering various aspects of neuroscience, followed by a week of experimenting in the lab, the students get a true feel of a life in…

  • Key mechanisms identified for improving astrocyte-to-neuron reprogramming

    Researchers from the Ludwig Maximilian University of Munich (LMU) made significant progress in unraveling novel mechanisms of glia-to-neuron conversion. By using novel methods in epigenome profiling, they identify a posttranslational modification of Neurogenin2 which profoundly impacts epigenetic rewiring and the improvement in neuronal programming. Specifically, they identified a novel protein as key player in this…

  • Amyloidosis triggers age-related oligodendrocyte and myelin damage

    Age-related myelin damage leads to white matter inflammation, but its impact on chronic neurodegenerative diseases remains unclear. A recent study reveals that amyloidosis alone can cause age-related oligodendrocyte and myelin damage in mouse models of Alzheimer’s disease. The research team discovered that CD8 T cells contribute to neurodegenerative diseases associated with amyloidosis by abnormally activating…

  • TRR 274 at Munich Brain Day 2024

    The TRR 274 was present once again at the second edition of the Munich Brain Day. The event aimed at bringing the neuroscientist community in Munich together is co-organized by TRR project leader Ruben Portugues. This year, Simon Schäfer and Mikael Simons from our TRR were invited speakers. During the poster session, several of our…