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    Magdalena Götz Awarded the Bavarian Order of Merit

    TRR 274 Project leader Prof. Magdalena Götz has been awarded the Bavarian Order of Merit by Minister President Dr. Markus Söder.Read the article written by the Helmholtz

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    Microscopy course in Bordeaux

    Several members of our TRR 274 were co-organizing and teaching at the advanced imaging techniques course in Bordeaux from 30 Sept to 18 Oct 2024. Francesca

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    CD8+ T cells drive inflammation in both prodromal and established MS

    Exciting new research is shedding light on the role of CD8+ T cells in MS, revealing how they contribute to disease progression.Using single-cell RNA sequencing and

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    BCAS1+ oligodendrocytes enable efficient cortical remyelination in multiple sclerosis

    BCAS1-positive oligodendrocytes enable efficient cortical remyelination in multiple sclerosis

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    Fig. 9: Proposed mechanisms by which TFEB governs B-lymphoid fate decisions.

    TFEB governs B-lymphoid fate decisions.

    TFEB activation hallmarks antigenic experience of B lymphocytes and directs germinal center fate decisions Antigenic stimulation triggers TFEB to move into the nucleus, where it can

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    Oligodendroglial glucose starvation leads to a gradual myelin loss.

    Oligodendroglial fatty acid metabolism as a central nervous system energy reserve

    A recent study published in Nature Neuroscience reveals that oligodendrocytes, the myelinating cells of the central nervous system (CNS), play a crucial role in energy metabolism

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    ERC Starting Grant for Anna-Sophia Wahl

    Congratulations to Anna-Sophia Wahl for obtaining a European Research Council (ERC) Starting Grant! From the Ludwig-Maximilians-Universität München Newsroom:”In the ARISE (Activate Repair In StrokE) project, Anna-Sophia Wahl wants

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    Florence Bareyre

    Congratulations Professor Bareyre!

    After her outstanding contributions to research and teaching, our project leader Florence Bareyre has been awarded an adjunct professorship.

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    Multi-cellular response

    TRR 274 Lecture Series – Winter Semester 2024/25

    Lecture Series

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    neuronal reprogramming

    Key mechanisms identified for improving astrocyte-to-neuron reprogramming

    Researchers from the Ludwig Maximilian University of Munich (LMU) made significant progress in unraveling novel mechanisms of glia-to-neuron conversion. By using novel methods in epigenome profiling,

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    Age-related myelin damage

    Amyloidosis triggers age-related oligodendrocyte and myelin damage

    Age-related myelin damage leads to white matter inflammation, but its impact on chronic neurodegenerative diseases remains unclear. A recent study reveals that amyloidosis alone can cause

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    Autoimmune diseases, Human thymus

    Possible trigger for autoimmune diseases discovered

    Immune system: B cells teach T cells which targets must not be attacked

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